Climara Patch (Estradiol Hemihydrate)

Brand name: Climara patch, Femseven
Generic name: Estradiol Hemihydrate
Used for: Providing relief from the symptoms of menopause and prevention of osteoporosis
Availability: Brand Climara patch (Bayer) 25mcg, 50mcg, 75mcg, 100 mcg

How Estradiol Works

Climara is a medicated patch that contains the hormone estrogen (estradiol), the same hormone that is produced naturally in the body. Climara is used to provide relief from the symptoms of menopause such as feelings of warmth in the face, neck and chest, or sudden intense episodes of heat and sweating (hot flushes) which can cause sleep disturbance leading to fatigue, irritability and depression. These symptoms are caused by the body making less estrogen. Estradiol also helps prevent from developing osteoporosis (thin weak bones). When you place this patch on your skin, the hormone is transferred to your body through your skin.

Generic Climara patch vs Brand Climara patch

Brand and generic Climara patch are available with a doctor’s prescription. It is entirely your choice whether you want a brand or generic. The pharmaceutical company Bayer markets Estradiol as Climara patch in North America. Brand Climara patch and generic Climara patch are identical in dose, strength, safety, efficacy and its intended use. The biggest difference is that the generic is not manufactured inside a Bayer facility. Rest assured that Blueskydrugs.com only provides you with highest quality generic drugs from reputable generic manufacturers. If you have any concerns, feel free to contact us.

Estradiol Possible side effects

Contact your doctor or pharmacist if you experience side effects and they are severe and bothersome. Most of the side effects are manageable and may go away on their own. Some of the common side effects include:

• Bloating;
• Breast pain, breast tenderness;
• Changes in genital bleeding pattern (including breakthrough bleeding and spotting);
• Localized darkening of the skin;
• Mood swings;
• Redness or mild irritation under or around the patch;
• Weight gain

Contact your doctor immediately if you notice any of the following symptoms:

• Abdominal pain;
• Changes in body weight;
• Heavy periods;
• Migraine headaches;
• Nausea or vomiting;
• Persistent skin irritation;
• Retention of fluid;
• Unexpected vaginal bleeding

Estradiol Guidelines

Do not use Climara patch if you: are pregnant or breastfeeding, have or have ever had liver disease, have a personal history of certain types of cancer, have overgrowth of the lining of the uterus, have experienced undiagnosed genital bleeding, have heart diseases, have a personal history of blood clots, were born with certain blood clotting disorder, have had partial or complete loss of vision, have had an allergic reaction to estrogen; Before you begin to use Climara, talk to your doctor if you: have allergy or intolerance to any medications or other substances, have breast disease, have experienced any unusual vaginal bleeding, have a history of uterine fibroids, have a liver disease, jaundice or itching related to estrogen use or during pregnancy, have or have had yellow-brown patches on the skin; have inherited deafness, have episodes of rapid swelling of hands, feet, face, eyes, tongue, throat (airway blockage), or digestive tract, have a history of migraine headache, need long bed rest, have a history of kidney disease, bone disease, asthma or epilepsy, have diabetes, have high prolactin levels, have high cholesterol or high triglycerides, are pregnant or are breastfeeding, have had a surgical removal of the uterus, smoke, have a history of depression. The following may counteract with Estradiol, so make sure to tell your doctor about any prescription and over-the-counter medications you are taking.

• Anticoagulants, antidiabetic agents drugs used for the treatment of certain heart diseases or high blood pressure (eg, diltiazem, verapamil);
• Alcohol, grapefruit juice and St. John’s wort;
• Antibiotics (eg, erythromycin, clarithromycin, penicillin, tetracycline);
• Antifungals (eg, griseofulvin, fluconazole, itraconazole, ketoconazole, voriconazole);
• Antivirals (ritonavir);
• Barbiturates, carbamazepine, meprobamate, phenylbutazone, primidone, phenytoin, oxcarbazepine, topiramate, felbamate or rifampicin;
• Drugs used for the treatment of HIV infections and Hepatitis C Virus infections (e.g., nelfinavir, ritonavir, ritonavir-boosted protease inhibitors, boceprevir, telaprevir, nevirapine)